To be eligible for the BSc degree program at St. Charles College of Education in Madurai, candidates must have completed their higher secondary education (10+2) with a minimum aggregate of 50% in the science stream. Additionally, candidates must have studied subjects such as Physics, Chemistry, and Mathematics/Biology. Admission is granted based on merit, and candidates may also have to clear an entrance exam conducted by the college. It is important for applicants to meet the eligibility criteria set by the college in order to be considered for admission to the BSc program.